•Naltrexone is a long-acting opioid antagonist used to treat a wide variety of inflammatory conditions in multiple organ systems. Evidence supports the use of low-dose naltrexone in Hailey-Hailey disease and full therapeutic doses may have a role in treating a…

Treatment failures after noninvasive therapy for superficial basal-cell carcinoma are frequently of a non-superficial subtype. These non-superficial treatment failures probably result from underdiagnosed aggressive components in primary tumors, not from transformation; they were less frequently observed following imiquimod than after…

The accuracy of dermoscopy for basal cell carcinoma (BCC) has not been systematically studied. Dermoscopy is a sensitive and specific add-on tool for the diagnosis of BCC, especially for the pigmented variant. Dermoscopy training should be included in dermatology residency…

Desmoplastic melanoma (DM) represents an infrequently occurring and distinct histologic pattern of melanomas, often lacking mutations in genes typically altered in conventional melanomas including BRAF, NRAS, and KIT.We aimed at better characterizing the genetic profile of this subgroup of melanomas…